Hello all.
testing Applocker through Intune, I was able to create a device management profile to lock a device down and it seemed to work well.
However..
Then I tried to create a device configuration profile to remove the configuration and unlock the device which caused the device to lock up and become unusable with no access to the desktop.
If I deleted the contents of the windows system32 applocker is seemed to give me access briefly, then it seemed to bring the config back and it was locked down again until it failed to get to the desktop again.
Has anyone else done this without trouble?